http://hdl.handle.net/10288/1114 Theses and Dissertations of William & Mary Schools and Departments other than VIMS Search the Channel search http://dspace.swem.wm.edu/simple-search http://hdl.handle.net/10288/1593 Title: A Study of the Effects of the Return of World War II Veterans on Collegiate Football in the Southern Conference<br/><br/>Authors: Creekmur, Louis<br/><br/>Description: This thesis is not yet available online pending approval of the copyright holder. The purposes of the study are to determine the effects of the return of World War II veterans on collegiate football in the Southern Conference during the immediate post-war years (1946-1949) in regard to (1) coaching procedures, (2) training regulations, (3) practice schedules, (4) actual gam conditions, and (5) scheduling of football games between colleges. http://hdl.handle.net/10288/1560 Title: To Be Amiable and Accomplished: Fitting Young Women for Upper-Class Virginia Society 1760-1810<br/><br/>Authors: Eberlein, Tori<br/><br/>Description: Young women needed to be equipped with suitable skills and attitudes in order to assume their adult role in upper-class Virginia society (1760-1810). Prescriptive writings of parents, relatives, and friends, and guidelines found in widely-published ladies morality books provided an outline of the ideal qualities a young woman should posses. Literacy, particularly the ability to write well, was a vital part of a young woman's education. Although a young woman was supposed to study some academic subjects, such as geography and French, other areas of study were thought to be unsuitable. Musical training, dancing and drawing were widely encouraged accomplishments. Ideally, appropriate education and social training produced young women who were loved and admired in Virginia society. http://hdl.handle.net/10288/1471 Title: Targeting the Sodium Iodide Symporter for In Vivo Detection and Characterization of Mammary Tumors in the Murine Model Using a Novel Gamma Camera<br/><br/>Authors: Blue, Randall Eric<br/><br/>Description: Effective diagnosis and treatment of breast cancer rely on a precise and detailed understanding of the cellular-molecular alterations that give rise to an oncogenic phenotype. With the advent of new imaging technologies investigators have begun to follow mammary tumor development in vivo and noninvasively with high resolution and sensitivity. Continued progress requires combining molecular biology and imaging with the goal of imaging the metabolism of specific tumor-related molecules. As a result, we have developed a novel small animal gamma camera that is capable of detecting low levels (0.52 MBq, 14 uCi) of radioiodine (125^I). The dynamic uptake of radioiodine through the sodium iodide symporter (NIS) was used to detect the progression of spontaneous mammary tumors in the mouse mammary tumor virus (MMTV) model as well as the transgenic animal model expressing the polyoma middle T oncoprotein (PyVT). Based on whole mount immunohistochemistry, NIS protein expression correlates with the gamma camera images of radioiodine uptake, which is also a promising radiotracer for detecting small, non-palpable tumors (3 mm). Additionally, gamma imaging was capable of identifying PyVT mice from their wild type littermates based upon their ability to accumulate radioiodine in nulliparous mammary glands as early as 5 weeks of age. MMTV tumors are classified into three groups based on their unique radioiodine distribution that is correlated with tumor size, but not propagation rate. Differences in radioiodine uptake gain (or loss) are dynamic especially during early dose administration. Finally, mammary glands show differences in uptake pattern when a tumor is present. Taken together, these results suggest that radioiodide imaging is a promising in vivo method for monitoring the changes associated with tumor development such as changes of tumor size, pattern, and aspects of gene-specific metabolism over both short and long durations. Our results also indicate that the classifiable heterogeneity present in dynamic gamma camera images may correlate with specific patterns or signatures of gene expression that, in turn, indicate tumor subtype and progression. These data may allow investigators to develop an effective and sensitive system of in vivo imaging of molecules and metabolism that reflect the molecular signature of a tumor in real time. Our system may provide a means for early detection, ideally even a precancerous state before malignancy develops, and a method to assess the overall state of a tumor with the goal of predicting the best therapeutic regime and following the efficacy of the therapy in real time by examining specific molecular targets. http://hdl.handle.net/10288/1135 Title: A Study of the Administration of an Educational Institution<br/><br/>Authors: Story, William Joseph, 1909-<br/><br/>Abstract: The print version is considered the official and archival copy of this dissertation or thesis. Researchers are encouraged to consult the archival copy of this dissertation or thesis when citing this work. http://hdl.handle.net/10288/1134 Title: The Connection Between Qualities of Effective Teachers and Selection Interviews : The Development of a Teacher Selection Interview Protocol<br/><br/>Authors: Hindman, Jennifer L., 1971-<br/><br/>Abstract: The purpose of this study was to synthesize the extant research literature on qualities of effective teachers and selection interviews as a step in developing an instrument that included an anchored rating scale that was validated through a national survey. The survey, which was sent to 300 practicing principals, collected information on building-level administrators’ interviewing practices and their perceptions of statements associated with varying levels of teacher effectiveness. Principals reported that they often use techniques that enhance the validity and reliability of the interview. Descriptive statistics summarized the level of agreement among administrators on how they rated statements as well as the degree to which their ratings agreed with a research-based targeted rating. A MANOVA found significant interactions for interviewer training and the use of specific interviewing techniques. Finally, correlations and chi-square tests established that administrator demographics had little impact on how they rated a series of statements associated with teacher responses to interview questions.The print version is considered the official and archival copy of this dissertation or thesis. Researchers are encouraged to consult the archival copy of this dissertation or thesis when citing this work.